Flight or Fight


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Flight or Fight

Remember the object is not to avoid our feelings, which are not helpful, but rather to acknowledge and honour them. Suffering comes from trying to avoiding feelings. But simply acknowledging what we are feeling is not enough it is also important to know what to do when we acknowledge them, how to sooth and calm ourselves.

How the Fight or Flight Response Works

How do you comfort and sooth yourself? What practices do you use, maybe there are cultural or spiritual practices you use that help you calm yourself, such as smudging, drumming, chanting or singing, praying, deep breathing, walking, stretching, writing, talking, listening to music.

While skeletal biologist Gerard Karsenty of Columbia University does not have the answers, he certainly has a theory. Karsenty has been studying osteocalcin for more than two decades.

As well as being one of the most abundant proteins in the body, he says, osteocalcin is important for a variety of physiological functions including memory retention, capacity for exercise, testosterone production, and insulin secretion. In these seemingly disparate functions, Karsenty sees a link.

In all cases, the stressors invoked a significant rise in the circulating levels of osteocalcin, but not of other bone hormones.

It certainly emphasizes. Because the basolateral amygdala of the brain is thought to recognize, interpret, and process such stressors, Karsenty and colleagues investigated whether this brain region controlled osteocalcin release.


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Sure enough, when they inhibited neuronal activity in the basolateral amygdala of mice, osteocalcin levels no longer spiked in response to a stressor. The team went on to show that mice lacking osteocalcin had a diminished stress response and that injection of the hormone in the animals was enough to evoke fight-or-flight physiological markers.

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